Welcome to the homepage of the Kern LabOur research focuses on variation among individuals in the genomes of humans, fruit flies, and plants. In particular we are interested in the role that natural selection has played in shaping patterns of genome variation. Look around you- casual observation of the natural world leads to the intuition that organisms are superbly adapted to their environments. We are interested in dissecting these adaptations at the genomic level, and in turn learning about the nature of the adaptive process. To this end we use computational and mathematical approaches towards using genome sequence data for evolutionary inference.